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Research

Better questions start with better measurements

Ventos grew out of a device originally called “Smart Underwear,” developed by Professors Brantley Hall and Santiago Botasini at the University of Maryland to monitor hydrogen in flatus during daily life. Now we’re exploring how everyday gas patterns relate to food, microbes, and how people feel.

The first studies · Published in 2025

First, could we measure gas in everyday life

Nineteen participants wore Smart Underwear during waking hours for a week. We then tested whether it could detect a change after added fiber in the 38-person GUMDROP study. These early studies measured daytime patterns, not overnight gas.

GUMDROP · 38 participants

Low fiber. High fiber
A measurable difference

Participants followed a low-fiber diet and consumed control gumdrops on one day and inulin-containing gumdrops on the next. They wore Smart Underwear for eight hours after each challenge.

The Microbiome Activity Index increased with inulin in 36 of 38 participants. This demonstrates that the sensing technology behind Ventos can detect a gas response to added fermentable fiber.

The connected pairs show how much each person’s recorded hydrogen activity changed. Responses varied substantially, even under the same study protocol.

The index is a proxy for gas volume. It is not a good-or-bad score: more gas after fermentable fiber does not, by itself, mean worse gut health.

Read the published Smart Underwear study ↗

Low fiber versus added inulin: paired results for 38 participantsEach line connects one participant’s microbiome activity index on the control and inulin days. Thirty-six of 38 increased. Linear scale from zero to 3,000. This index is a proxy for gas volume.05001,0001,5002,0002,5003,000Microbiome Activity IndexLow fiberAdded inulin fiberControl gumdropsInulin gumdrops
Each line connects one participant’s results on the two days. Blue lines increased; muted red lines decreased. Both days used a low-fiber background diet; the higher-fiber challenge added inulin.

Lactose study · DDW 2026 abstract and poster

Producing gas and noticing it are different

In a randomized, double-blind crossover study, 37 participants consumed 20 grams of lactose on one day and 20 grams of sucrose on another, with eight hours of recording after each challenge.

Among the 24 participants classified as intervention responders, the day with higher measured activity was the lactose day in 22 cases. Reports of excessive flatulence identified it in 12.

Objective measurements and symptom reports capture different parts of the experience. Measuring both gives us a fuller picture.

Read the Medical Daily coverage ↗

Which day was the lactose day

Device measurements22/24 · 92%
Symptom reports12/24 · 50%
Results among 24 intervention responders, defined by a greater than 1.5-fold difference in measured activity between challenge days. These are challenge-day classification results, not diagnostic accuracy for lactose intolerance. Presented at Digestive Disease Week 2026.

Ventos × LOAM · Completed validation study

Three interventions
Distinct gas responses

We recently completed a double-blind, placebo-controlled validation study with more than 90 participants, comparing inulin, LOAM, and cellulose.

Ventos measurements clearly differentiated the gas responses to the three interventions.

Preliminary findings

More than 90 participants.
Inulin. LOAM. Cellulose.

A blinded comparison of how different interventions affect measured gas patterns.

The Human Flatus Atlas

It’s 2026. We still lack a clear baseline for human gas patterns

How often do people fart in everyday life? How much do patterns vary from person to person, with meals, and across the day and night? Small studies and self-reports have left major gaps in this basic knowledge.

The Human Flatus Atlas is working to establish that baseline through continuous measurements in everyday life, alongside meal photos and reports of digestive symptoms.

95.1%

of Human Flatus Atlas respondents said Ventos was comfortable to wear.

Explore the Human Flatus Atlas ↗

  • Establish reference ranges for daily flatus patterns.
  • Map variation between people, with diet, and across day and night.
  • Understand how measured gas relates to what people feel.

Help us discover how Zen Digestion works

The Zen Digester Study pairs Ventos recordings with Tiny Health microbiome testing. Receive your personal gas profile, full Tiny Health results, and a combined report while helping us investigate why gas patterns differ.

Explore the $349 study bundle

The study explores relationships. It has not established that Ventos improves food tolerance or treats symptoms. Ventos is for research and general wellness.